Self-administering cannabinoids.
نویسندگان
چکیده
Endocannabinoids, which are typically released by principal cells in response to prolonged depolarization, act as retrograde messengers to inhibit synaptic transmission. A recent study shows that in a specific subtype of cortical interneuron, endocannabinoids released under similar circumstances can also act cell-autonomously. Here, endocannabinoids endow these neurons with a memory of their own activity in the form of a long-term change in excitability.
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عنوان ژورنال:
- Trends in neurosciences
دوره 28 7 شماره
صفحات -
تاریخ انتشار 2005